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Asbestos Mesothelioma Cancer Clinical Trials

The US Government keeps an online database, at clinicaltrials.gov, of clinical research studies for Mesothelioma cancer, but doesn't review or approve the safety and science of these trials. The website is maintained by the National Library of Medicine (NLM). The links below go to the clinical trial information on clinicaltrials.gov. Talk with your health care professional about possible risks and benefits before joining any studies.

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

Fri, 13 Jun 2025 00:00:00 EDT

Conditions: Mesothelioma; Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Ovarian Neoplasms; Lung Neoplasms; Thymus Neoplasms; Colonic Neoplasms
Interventions: Device: mesothelin expression testing; Biological: TNhYP217 CAR T Cells; Drug: fludarabine; Drug: cyclophosphamide
Sponsors: National Cancer Institute (NCI)
Not yet recruiting

Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma

Fri, 13 Jun 2025 00:00:00 EDT

Conditions: Mesothelioma; Malignant Mesothelioma (MM); Early-stage Mesothelioma; Subclinical Mesothelioma; BRCA1-Associated Protein-1 (BAP1) Mutations; Early-stage BAP1-associated Malignancies
Interventions: Drug: alrizomadlin
Sponsors: National Cancer Institute (NCI)
Not yet recruiting

Immune Microenvironment and Gene Expression Profiling in Mesothelioma

Thu, 5 Jun 2025 00:00:00 EDT

Conditions: Mesothelioma; Mesotheliomas Pleural; Mesothelioma; Lung
Interventions: Other: Translation analysis
Sponsors: Istituto Oncologico Veneto IRCCS
Recruiting

Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors

Wed, 4 Jun 2025 00:00:00 EDT

Conditions: Malignant Mesothelioma; Metastatic Malignant Solid Tumor; Advanced Solid Tumor
Interventions: Drug: ISM6331
Sponsors: InSilico Medicine Hong Kong Limited
Recruiting

MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma

Wed, 11 Jun 2025 00:00:00 EDT

Conditions: Unresectable Pleural Mesothelioma
Interventions: Drug: Volrustomig; Drug: Pemetrexed; Drug: Carboplatin; Drug: Cisplatin; Drug: Nivolumab; Drug: Ipilimumab
Sponsors: AstraZeneca
Recruiting

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

Sun, 8 Jun 2025 00:00:00 EDT

Conditions: Malignant Peritoneal Mesothelioma; Peritoneal Mesothelioma; Mesothelioma; Mesothelioma, Malignant; Malignant Mesothelioma
Interventions: Drug: Pemetrexed; Drug: Cisplatin; Drug: Carboplatin
Sponsors: Memorial Sloan Kettering Cancer Center
Recruiting

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

Fri, 6 Jun 2025 00:00:00 EDT

Conditions: Mesothelioma; Malignant Mesothelioma (MM); Early-stage Mesothelioma; Subclinical Mesothelioma; BRCA1-Associated Protein-1 (BAP1) Mutations; Early-stage BAP1-associated Malignancies
Interventions: Drug: Decitabine/cedazuridine
Sponsors: National Cancer Institute (NCI)
Recruiting

HTL0039732 in Participants With Advanced Solid Tumours

Sun, 8 Jun 2025 00:00:00 EDT

Conditions: Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stomach Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Colorectal Neoplasms; Pancreatic Neoplasms; Lung Neoplasms; Urinary Bladder Neoplasms; Mesothelioma, Malignant; Uterine Cervical Neoplasms; Kidney Neoplasms; Sarcoma; Pheochromocytomas
Interventions: Drug: HTL0039732 Capsules; Drug: HTL0039732 Capsules and atezolizumab infusion
Sponsors: Cancer Research UK; Nxera Pharma UK Limited
Recruiting

Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

Wed, 11 Jun 2025 00:00:00 EDT

Conditions: Advanced Renal Cell Carcinoma; Advanced Mesothelioma; Advanced Osteosarcoma
Interventions: Drug: CAR.70/IL15-transduced CB-derived NK cells; Drug: Fludarabine phosphate; Drug: Cyclophosphamide
Sponsors: M.D. Anderson Cancer Center
Recruiting

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

Thu, 5 Jun 2025 00:00:00 EDT

Conditions: High Grade Epithelial Ovarian Cancer; High Grade Serous Ovarian Cancer; Primary Peritoneal Carcinoma; Fallopian Tube Cancer; Endometrial Cancer; Non-small Cell Lung Cancer; Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (NSCLC); Mesothelioma; Breast Adenocarcinoma; Triple Negative Breast Cancer; Hormone Receptor-positive/Her2 Negative Breast Cancer; Platinum-resistant Ovarian Cancer (PROC); Platinum Sensitive Ovarian Cancer (PSOC); Primary Refractory Ovarian Cancer; Uterine Cancer
Interventions: Drug: Rina-S; Drug: Carboplatin; Drug: Bevacizumab; Drug: Pembrolizumab
Sponsors: Genmab
Recruiting