Mesothelioma Research News

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ScienceDaily

https://www.sciencedaily.com/news/health_medicine/mesothelioma/ Read the medical research on mesothelioma including mesothelioma symptoms and treatments. Information on mesothelioma and asbestos. en-us Fri, 11 Jul 2025 00:17:12 EDT Fri, 11 Jul 2025 00:17:12 EDT 60 https://www.sciencedaily.com/images/scidaily-logo-rss.png https://www.sciencedaily.com/news/health_medicine/mesothelioma/ For more science news, visit ScienceDaily. https://www.sciencedaily.com/releases/2024/09/240912135720.htm New study and promising results from the first clinical trial in patients provide novel insights and new hope for one of the deadliest of cancers. Thu, 12 Sep 2024 13:57:20 EDT https://www.sciencedaily.com/releases/2024/09/240912135720.htm https://www.sciencedaily.com/releases/2024/09/240905120935.htm A cancer study found that certain gut bacteria may influence whether or not a patient's immune system is successful in fighting mesothelioma, an aggressive form of cancer. Thu, 05 Sep 2024 12:09:35 EDT https://www.sciencedaily.com/releases/2024/09/240905120935.htm https://www.sciencedaily.com/releases/2024/02/240215113546.htm An innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but rapidly fatal type of cancer with few effective treatment options. Thu, 15 Feb 2024 11:35:46 EST https://www.sciencedaily.com/releases/2024/02/240215113546.htm https://www.sciencedaily.com/releases/2023/11/231114143823.htm A new study has discovered asbestos exposure led to a higher incidence of asbestos-related lung cancers in British and Australian naval personnel than in other armed forces. Tue, 14 Nov 2023 14:38:23 EST https://www.sciencedaily.com/releases/2023/11/231114143823.htm https://www.sciencedaily.com/releases/2023/10/231017143617.htm Researchers have developed a human in vitro model that closely mimics the complexities of radiation-induced lung injury (RILI) and radiation dose sensitivity of the human lung. Using a previously developed microfluidic human Lung Alveolus Chip lined by human lung alveolar epithelial cells interfaced with lung capillary cells to recreate the alveolar-capillary interface in vitro, the researchers recapitulated many of the hallmarks of RILI, including radiation-induced DNA damage in lung tissue, cell-specific changes in gene expression, inflammation, and injury to both the lung epithelial cells and blood vessel-lining endothelial cells. By also evaluating the potential of two drugs to suppress the effects of acute RILI, the researchers demonstrated their model's capabilities as an advanced, human-relevant, preclinical, drug discovery platform. Tue, 17 Oct 2023 14:36:17 EDT https://www.sciencedaily.com/releases/2023/10/231017143617.htm https://www.sciencedaily.com/releases/2023/06/230608120900.htm The largest and most comprehensive cell map of the human lung has been completed. The Human Lung Cell Atlas reveals the great diversity of cell types in the lung and shows key differences between health and disease. Researchers identified rare cell types and found common cell states between lung fibrosis, cancer and COVID-19, offering new ways of understanding lung disease, which could help identify new therapeutic targets. Thu, 08 Jun 2023 12:09:00 EDT https://www.sciencedaily.com/releases/2023/06/230608120900.htm https://www.sciencedaily.com/releases/2022/12/221214113907.htm Researchers found that treating patients who have resectable malignant pleural mesothelioma, meaning that their tumor can be removed with surgery, with immunotherapy ahead of surgery resulted in favorable clinical outcomes. Wed, 14 Dec 2022 11:39:07 EST https://www.sciencedaily.com/releases/2022/12/221214113907.htm https://www.sciencedaily.com/releases/2022/09/220920145440.htm In lab experiments, researchers observed a molecule called EGCG break up tau tangles extracted from Alzheimer's disease brain tissue EGCG does not, however, easily penetrate the human brain. They found two other molecules -- CNS-11 and CNS-17 -- that work like EGCG to stop tangles spreading cell to cell but are better leads for drugs. Tue, 20 Sep 2022 14:54:40 EDT https://www.sciencedaily.com/releases/2022/09/220920145440.htm https://www.sciencedaily.com/releases/2022/09/220913110412.htm A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year. Tue, 13 Sep 2022 11:04:12 EDT https://www.sciencedaily.com/releases/2022/09/220913110412.htm https://www.sciencedaily.com/releases/2022/08/220822174924.htm Researchers have shown they can eradicate advanced-stage mesothelioma tumors in mice in just a few days with a treatment combining tiny, cytokine 'drug factory' implants and a checkpoint inhibitor drug. Mon, 22 Aug 2022 17:49:24 EDT https://www.sciencedaily.com/releases/2022/08/220822174924.htm https://www.sciencedaily.com/releases/2022/08/220818091242.htm A 'state of the science' review details the most reported symptoms of 6 cardiovascular diseases (CVDs): heart attack, heart failure, valve disease, stroke, heart rhythm disorders, and peripheral artery and vein disease (PAD and PVD). There are important differences in symptoms between women and men. Depression, common across many CVDs, may influence a person's ability to detect changes in symptoms. Effective methods of monitoring and measuring symptoms over time are critical to manage cardiovascular disease well and prevent or delay its progression. Thu, 18 Aug 2022 09:12:42 EDT https://www.sciencedaily.com/releases/2022/08/220818091242.htm https://www.sciencedaily.com/releases/2022/03/220330103247.htm Researchers have discovered that a protein critical in the embryonic stages of life is reactivated in certain cases of mesothelioma, offering clues into the origin of this aggressive cancer. Wed, 30 Mar 2022 10:32:47 EDT https://www.sciencedaily.com/releases/2022/03/220330103247.htm https://www.sciencedaily.com/releases/2022/02/220224161754.htm Asbestos fibers can cause lung cancer and other diseases, often multiple decades following exposure. Many researchers have sought to elucidate disease mechanisms, but a new study took the opposite approach, using a high-tech microscope to look at how the mineral changed upon interaction with lung cells. Their findings suggest that the mineralogical transformations inside the cells may play a role in triggering disease. Thu, 24 Feb 2022 16:17:54 EST https://www.sciencedaily.com/releases/2022/02/220224161754.htm https://www.sciencedaily.com/releases/2021/12/211216145923.htm Researchers have discovered that a nanoparticle therapeutic enhances cancer immunotherapy and is a possible new approach in treating malignant pleural effusion (MPE). MPE is the accumulation of fluid between the chest wall and lungs and is accompanied by malignant cells and/or tumors. Thu, 16 Dec 2021 14:59:23 EST https://www.sciencedaily.com/releases/2021/12/211216145923.htm https://www.sciencedaily.com/releases/2021/11/211108130903.htm Combining the immunotherapy agent durvalumab with the chemotherapy agents pemetrexed and cisplatin or carboplatin may provide a new treatment option for patients who have inoperable pleural mesothelioma, a cancer of the tissues lining the lungs, according to a phase II clinical trial. Mon, 08 Nov 2021 13:09:03 EST https://www.sciencedaily.com/releases/2021/11/211108130903.htm https://www.sciencedaily.com/releases/2021/07/210714110422.htm A phase II study found that treatment with atezolizumab and bevacizumab was well-tolerated and resulted in a 40% objective response rate in patients with advanced malignant peritoneal mesothelioma, a rare cancer in the lining of the abdomen. Wed, 14 Jul 2021 11:04:22 EDT https://www.sciencedaily.com/releases/2021/07/210714110422.htm https://www.sciencedaily.com/releases/2021/03/210326085230.htm International genomics research has used artificial intelligence (AI) to study an aggressive form of cancer, which could improve patient outcomes. Fri, 26 Mar 2021 08:52:30 EDT https://www.sciencedaily.com/releases/2021/03/210326085230.htm https://www.sciencedaily.com/releases/2020/12/201218131852.htm Researchers have developed a novel type of nanoparticle that efficiently and selectively kills cancer cells, thus opening up new therapeutic options for the treatment of tumors. Fri, 18 Dec 2020 13:18:52 EST https://www.sciencedaily.com/releases/2020/12/201218131852.htm https://www.sciencedaily.com/releases/2020/10/201026114220.htm Gold nanotubes - tiny hollow cylinders one thousandth the width of a human hair - could be used to treat mesothelioma, a type of cancer caused by exposure to asbestos, according to a team of researchers. Mon, 26 Oct 2020 11:42:20 EDT https://www.sciencedaily.com/releases/2020/10/201026114220.htm https://www.sciencedaily.com/releases/2020/07/200723115853.htm A new study found that lung ultrasound was highly sensitive for detecting abnormalities in patients with coronavirus disease (COVID-19), with B-lines, a thickened pleural line, and pulmonary consolidation the most commonly observed features. Additionally, the authors found that lung ultrasound features can be used to reflect both the infection duration and disease severity. Thu, 23 Jul 2020 11:58:53 EDT https://www.sciencedaily.com/releases/2020/07/200723115853.htm https://www.sciencedaily.com/releases/2020/06/200611152457.htm Inoperable malignant pleural mesothelioma, is a rare and aggressive cancer of the protective lining of the lungs, or pleura, often caused by exposure to asbestos. Thu, 11 Jun 2020 15:24:57 EDT https://www.sciencedaily.com/releases/2020/06/200611152457.htm https://www.sciencedaily.com/releases/2020/03/200317215628.htm Iron build-up in the lung cells and tissues is associated with worse asthma symptoms and lower lung function, according to new research. The researchers say that the study, which includes data from asthma patient samples and mouse models, is the first to definitively show a relationship between iron build-up in the lung cells and tissues and the severity of asthma. Tue, 17 Mar 2020 21:56:28 EDT https://www.sciencedaily.com/releases/2020/03/200317215628.htm https://www.sciencedaily.com/releases/2020/01/200129131424.htm Protective cells in the lungs of ex-smokers could explain why quitting smoking reduces the risk of developing lung cancer. Scientists have discovered that compared to current smokers, people who had stopped smoking had more genetically healthy lung cells, which have a much lower risk of developing into cancer. Wed, 29 Jan 2020 13:14:24 EST https://www.sciencedaily.com/releases/2020/01/200129131424.htm https://www.sciencedaily.com/releases/2019/09/190930082253.htm Patients with mesothelioma may gain similar benefit from immunotherapy as chemotherapy, and good responders may provide important clues to novel treatment for the thousands of new cases each year. New data highlight the need to understand the biological mechanisms whereby mesothelioma, which is incurable, adapts to immunotherapy in some patients but not in others, resulting in variations in treatment response. Mon, 30 Sep 2019 08:22:53 EDT https://www.sciencedaily.com/releases/2019/09/190930082253.htm https://www.sciencedaily.com/releases/2019/08/190806121813.htm Researchers for the first time have combined a powerful microscopy technique with automated image analysis algorithms to distinguish between healthy and metastatic cancerous tissue without relying on invasive biopsies or the use of a contrast dye. This new approach could one day help doctors detect cancer metastasis that is otherwise difficult to see via standard imaging technologies during operations. Tue, 06 Aug 2019 12:18:13 EDT https://www.sciencedaily.com/releases/2019/08/190806121813.htm https://www.sciencedaily.com/releases/2019/04/190429125437.htm Mesothelioma patients are twice as likely to survive for two years or longer, if they are treated with a high dose of radiation to the affected side of the trunk. Mon, 29 Apr 2019 12:54:37 EDT https://www.sciencedaily.com/releases/2019/04/190429125437.htm https://www.sciencedaily.com/releases/2019/03/190331192535.htm A chimeric antigen receptor (CAR) T-cell therapy that targets the protein mesothelin showed no evidence of major toxicity and had antitumor activity in patients with malignant pleural disease from mesothelioma, according to new results. Sun, 31 Mar 2019 19:25:35 EDT https://www.sciencedaily.com/releases/2019/03/190331192535.htm https://www.sciencedaily.com/releases/2018/05/180529140930.htm Engineers have developed pressure-sensing photonic fibers that they have woven into a typical compression bandage. As the bandage is stretched, the fibers change color. Using a color chart, a caregiver can stretch a bandage until it matches the color for a desired pressure, before, say, wrapping it around a patient's leg. Tue, 29 May 2018 14:09:30 EDT https://www.sciencedaily.com/releases/2018/05/180529140930.htm https://www.sciencedaily.com/releases/2018/04/180402142458.htm Investigators have found that combined treatment with two cancer immunotherapy drugs -- one a novel immune modulator and one that focuses and activates the anti-tumor immune response -- significantly prolonged survival in mouse models of the aggressive cancer malignant mesothelioma. Mon, 02 Apr 2018 14:24:58 EDT https://www.sciencedaily.com/releases/2018/04/180402142458.htm https://www.sciencedaily.com/releases/2018/03/180308160528.htm Long, pointed asbestos fibers induce chronic inflammation, which can lead to cancer. Researchers have found underlying mechanisms for this and hope their results will help prevent damage. Thu, 08 Mar 2018 16:05:28 EST https://www.sciencedaily.com/releases/2018/03/180308160528.htm https://www.sciencedaily.com/releases/2018/02/180228092236.htm Lung cancer patients are particularly susceptible to malignant pleural effusion, when fluid collects in the space between the lungs and the chest wall. Researchers have discovered a novel mechanism that causes this to happen. Their study now refines the mechanistic picture. Wed, 28 Feb 2018 09:22:36 EST https://www.sciencedaily.com/releases/2018/02/180228092236.htm https://www.sciencedaily.com/releases/2017/11/171106132018.htm Researchers have shown for the first time in mice that long and thin nanomaterials called carbon nanotubes may have the same carcinogenic effect as asbestos: they can induce the formation of mesothelioma. The findings were observed in 10 percent -- 25 percent of the 32 animals included in the study, which has not yet been replicated in humans. Mon, 06 Nov 2017 13:20:18 EST https://www.sciencedaily.com/releases/2017/11/171106132018.htm https://www.sciencedaily.com/releases/2017/11/171102091118.htm A landmark study into the health impacts of living in a house with loose-fill asbestos insulation. Thu, 02 Nov 2017 09:11:18 EDT https://www.sciencedaily.com/releases/2017/11/171102091118.htm https://www.sciencedaily.com/releases/2017/09/170914152347.htm Investigators have uncovered a new genetic cause of mesothelioma: a genetic rearrangement in the ALK gene, observed in three patients with peritoneal mesothelioma. Unlike previously known causes, this new discovery points to a potential therapeutic approach for those few patients whose tumors harbor the mutation. Thu, 14 Sep 2017 15:23:47 EDT https://www.sciencedaily.com/releases/2017/09/170914152347.htm https://www.sciencedaily.com/releases/2017/08/170830141259.htm A team of researchers is the first to successfully bioengineer a functional lung with perfusable and healthy vasculature in an ex vivo rodent lung. Their new approach allows the removal of the pulmonary epithelium while maintaining the viability and function of the vascular network and the lung matrix. Wed, 30 Aug 2017 14:12:59 EDT https://www.sciencedaily.com/releases/2017/08/170830141259.htm https://www.sciencedaily.com/releases/2017/08/170830114757.htm Preventing injuries may not be the only reason children shouldn't use off-road vehicles (ORVs). In a new study, public health scientists raise concerns that people who use ORVs in many regions of the country may face exposure to hazardous mineral fibers. Wed, 30 Aug 2017 11:47:57 EDT https://www.sciencedaily.com/releases/2017/08/170830114757.htm https://www.sciencedaily.com/releases/2017/08/170803091928.htm A team of scientists has developed promising research towards a possible stem cell treatment for several lung conditions, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and cystic fibrosis -- often-fatal conditions that affect tens of millions of Americans. Thu, 03 Aug 2017 09:19:28 EDT https://www.sciencedaily.com/releases/2017/08/170803091928.htm https://www.sciencedaily.com/releases/2017/06/170627142030.htm Researchers have developed a new method for filling and sealing pleural cavities. The process consists of injecting polyurethane foams into the lungs with a self-expanding and self-modelling capacity that replaces aggressive surgical and palliative treatments used so far. Tue, 27 Jun 2017 14:20:30 EDT https://www.sciencedaily.com/releases/2017/06/170627142030.htm https://www.sciencedaily.com/releases/2017/06/170605110054.htm Malignant pleural mesothelioma or MPM is a rare cancer, but its incidence has been rising. This cancer is usually associated with asbestos exposure, and patients have a median life expectancy of only 13-15 months. All patients relapse despite initial chemotherapy, more than 50% of them within six months after stopping treatment. There are currently no effective therapeutic options for patients with MPM. Mon, 05 Jun 2017 11:00:54 EDT https://www.sciencedaily.com/releases/2017/06/170605110054.htm https://www.sciencedaily.com/releases/2017/05/170519084110.htm Patients with a hard-to-treat type of cancer are being given new hope in a ground-breaking clinical trial. Fri, 19 May 2017 08:41:10 EDT https://www.sciencedaily.com/releases/2017/05/170519084110.htm https://www.sciencedaily.com/releases/2017/05/170519083821.htm Lung cancer patients are particularly susceptible to malignant pleural effusion, when fluid collects in the space between the lungs and the chest wall. Researchers have discovered a novel mechanism that causes this to happen. Their study also shows that various active substances could potentially be used to treat this condition. Fri, 19 May 2017 08:38:21 EDT https://www.sciencedaily.com/releases/2017/05/170519083821.htm https://www.sciencedaily.com/releases/2017/03/170320115956.htm Pembrolizumab, an antibody drug already used to treat other forms of cancer, can be effective in the treatment of the most common form of mesothelioma, according to a new study. The work is the first to show a positive impact from checkpoint inhibitor immunotherapy drugs on this disease. Mon, 20 Mar 2017 11:59:56 EDT https://www.sciencedaily.com/releases/2017/03/170320115956.htm https://www.sciencedaily.com/releases/2016/12/161214145608.htm Patients with advanced malignant pleural mesothelioma (MPM) treated with a combination of surgery to remove the cancer but save their lung, plus photodynamic therapy and chemotherapy, had a median survival of nearly three years, with a subset of patients living longer than seven years, according to new research. Wed, 14 Dec 2016 14:56:08 EST https://www.sciencedaily.com/releases/2016/12/161214145608.htm https://www.sciencedaily.com/releases/2016/11/161122075955.htm The addition of a new type of fluid for use in peritoneal dialysis makes it easier to tolerate and protects the cells in the abdominal cavity. This could make the peritoneum more resilient to harmful effects, report investigators. Tue, 22 Nov 2016 07:59:55 EST https://www.sciencedaily.com/releases/2016/11/161122075955.htm https://www.sciencedaily.com/releases/2016/10/161024090344.htm Researchers have discovered a new option for treating malignant pleural mesothelioma. For the first time in the world, they were able to show in a preclinical study, both in the cell culture and in the animal model, that trabectedin, a chemotherapy drug that is already successfully used for other types of cancer, is also effective against malignant pleural mesothelioma. The active agent originally occurs in the Caribbean sea cucumber, a marine-dwelling tunicate. Mon, 24 Oct 2016 09:03:44 EDT https://www.sciencedaily.com/releases/2016/10/161024090344.htm https://www.sciencedaily.com/releases/2016/08/160824135519.htm Analysis of a large non-small cell lung cancer (NSCLC) patient cohort with stage IV M1a disease identified lymph node staging as having clinical significance and an impact on prognosis. Wed, 24 Aug 2016 13:55:19 EDT https://www.sciencedaily.com/releases/2016/08/160824135519.htm https://www.sciencedaily.com/releases/2016/08/160819153038.htm A new study challenges the long-held belief that asbestos fibers cannot move through soil. The findings have important implications for current remediation strategies aimed at capping asbestos-laden soils to prevent human exposure of the cancer-causing material. Fri, 19 Aug 2016 15:30:38 EDT https://www.sciencedaily.com/releases/2016/08/160819153038.htm https://www.sciencedaily.com/releases/2016/08/160808144904.htm A new study examined two classes of medications commonly prescribed to prevent cardiovascular events in dialysis patients and found no significant difference in outcomes. Mon, 08 Aug 2016 14:49:04 EDT https://www.sciencedaily.com/releases/2016/08/160808144904.htm https://www.sciencedaily.com/releases/2016/06/160624104754.htm One of the main functions of the kidneys is to filter metabolic products out of the blood. If the kidneys are no longer able to do this, the blood has to be artificially purified and drained of excess fluid. This is the purpose of dialysis. Now researchers are seeking new, better therapeutic approaches for those patients on dialysis. Fri, 24 Jun 2016 10:47:54 EDT https://www.sciencedaily.com/releases/2016/06/160624104754.htm https://www.sciencedaily.com/releases/2016/06/160614121314.htm Two classes of blood pressure medications are associated with a 16 percent lower risk of cardiovascular events in patients who are undergoing peritoneal dialysis. Tue, 14 Jun 2016 12:13:14 EDT https://www.sciencedaily.com/releases/2016/06/160614121314.htm https://www.sciencedaily.com/releases/2016/06/160609064753.htm Many mesothelioma patients avoid surgery for fear it will degrade their quality of life. But a study has found just the opposite: Patients who underwent an operation called pleurectomy and decortication (PD) generally reported their quality of life improved after surgery. Thu, 09 Jun 2016 06:47:53 EDT https://www.sciencedaily.com/releases/2016/06/160609064753.htm https://www.sciencedaily.com/releases/2016/04/160414113413.htm Immunotherapy with a live bacterium combined with chemotherapy demonstrated more than 90% disease control and 59% response rate in patients with malignant pleural mesothelioma (MPM), according to the results of a phase Ib trial. Thu, 14 Apr 2016 11:34:13 EDT https://www.sciencedaily.com/releases/2016/04/160414113413.htm https://www.sciencedaily.com/releases/2016/04/160411112554.htm Results of a small study of people with tingling pain in their hands and feet have added to evidence that so-called prediabetes is more damaging to motor nerves than once believed, report scientists. Mon, 11 Apr 2016 11:25:54 EDT https://www.sciencedaily.com/releases/2016/04/160411112554.htm https://www.sciencedaily.com/releases/2016/03/160314111127.htm A new drug is showing promise as a treatment for mesothelioma -- one of the most lethal cancers of all. The drug, known as HRX9, works by preventing the cancer cells from avoiding apoptosis -- the natural process by which unhealthy and damaged cells close themselves down and die. Mon, 14 Mar 2016 11:11:27 EDT https://www.sciencedaily.com/releases/2016/03/160314111127.htm https://www.sciencedaily.com/releases/2016/02/160229135143.htm In a comprehensive genomic analysis using more than 200 mesothelioma tumors, investigators have found previously unknown genetic alterations, including some that may be clinically actionable, as well as others that may improve diagnostics, screening and predictions about outcomes for patients. Mon, 29 Feb 2016 13:51:43 EST https://www.sciencedaily.com/releases/2016/02/160229135143.htm https://www.sciencedaily.com/releases/2016/02/160202185445.htm A new study suggests that significant improvements could be made in the scoring system physicians use to estimate the stage (severity) of mesothelioma, an aggressive and deadly cancer. Tue, 02 Feb 2016 18:54:45 EST https://www.sciencedaily.com/releases/2016/02/160202185445.htm https://www.sciencedaily.com/releases/2016/01/160129170452.htm The current issue of Technology and Innovation has articles on the 2015 Patents for Humanity Awards, asbestos exposure during outdoor recreational activities, the phenomenon of academic serial inventors, and a special section on regulatory science with articles on organic vs. conventional foods and the critical role of review criteria in peer review. Fri, 29 Jan 2016 17:04:52 EST https://www.sciencedaily.com/releases/2016/01/160129170452.htm https://www.sciencedaily.com/releases/2015/12/151222163106.htm Use of NSAIDs vs opiates resulted in no significant difference in measures of pain but was associated with more rescue medication (additional medicine needed due to uncontrolled pain) among patients with malignant pleural effusions (excess fluid accumulates around the lungs that is a complication of cancer) undergoing pleurodesis (a treatment for this condition that closes up the pleural space), according to a study. Tue, 22 Dec 2015 16:31:06 EST https://www.sciencedaily.com/releases/2015/12/151222163106.htm https://www.sciencedaily.com/releases/2015/09/150901095317.htm A new statistical model may help predict which patients are most likely to receive life-extending benefits from surgical treatment for malignant pleural mesothelioma, scientists say. Tue, 01 Sep 2015 09:53:17 EDT https://www.sciencedaily.com/releases/2015/09/150901095317.htm https://www.sciencedaily.com/releases/2015/07/150707093402.htm Aspirin may help mesothelioma patients, a new study suggests. The finding could eventually give doctors and patients a potential new tool to fight against this devastating disease, which kills about 3,200 people a year nationwide, and advance knowledge of how to fight other cancers. Tue, 07 Jul 2015 09:34:02 EDT https://www.sciencedaily.com/releases/2015/07/150707093402.htm

Breakthrough research extends hope for gastric cancer patients with peritoneal metasis

Thu, 12 Sep 2024 13:57:20 EDT

New study and promising results from the first clinical trial in patients provide novel insights and new hope for one of the deadliest of cancers.

Gut bacteria influence responses to immunotherapy in patients with asbestos related cancer

Thu, 05 Sep 2024 12:09:35 EDT

A cancer study found that certain gut bacteria may influence whether or not a patient's immune system is successful in fighting mesothelioma, an aggressive form of cancer.

New treatment for a rare and aggressive cancer improves survival rates in breakthrough clinical trial

Thu, 15 Feb 2024 11:35:46 EST

An innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but rapidly fatal type of cancer with few effective treatment options.

High lung cancer rates in naval veterans linked to asbestos

Tue, 14 Nov 2023 14:38:23 EST

A new study has discovered asbestos exposure led to a higher incidence of asbestos-related lung cancers in British and Australian naval personnel than in other armed forces.

Human Lung Chip leveraged to faithfully model radiation-induced lung injury

Tue, 17 Oct 2023 14:36:17 EDT

Researchers have developed a human in vitro model that closely mimics the complexities of radiation-induced lung injury (RILI) and radiation dose sensitivity of the human lung. Using a previously developed microfluidic human Lung Alveolus Chip lined by human lung alveolar epithelial cells interfaced with lung capillary cells to recreate the alveolar-capillary interface in vitro, the researchers recapitulated many of the hallmarks of RILI, including radiation-induced DNA damage in lung tissue, cell-specific changes in gene expression, inflammation, and injury to both the lung epithelial cells and blood vessel-lining endothelial cells. By also evaluating the potential of two drugs to suppress the effects of acute RILI, the researchers demonstrated their model's capabilities as an advanced, human-relevant, preclinical, drug discovery platform.

Single-cell atlas of the whole human lung

Thu, 08 Jun 2023 12:09:00 EDT

The largest and most comprehensive cell map of the human lung has been completed. The Human Lung Cell Atlas reveals the great diversity of cell types in the lung and shows key differences between health and disease. Researchers identified rare cell types and found common cell states between lung fibrosis, cancer and COVID-19, offering new ways of understanding lung disease, which could help identify new therapeutic targets.

Preoperative immunotherapy for mesothelioma shows favorable outcomes

Wed, 14 Dec 2022 11:39:07 EST

Researchers found that treating patients who have resectable malignant pleural mesothelioma, meaning that their tumor can be removed with surgery, with immunotherapy ahead of surgery resulted in favorable clinical outcomes.

Newly identified small molecules break amyloid tangles that cause Alzheimer's

Tue, 20 Sep 2022 14:54:40 EDT

In lab experiments, researchers observed a molecule called EGCG break up tau tangles extracted from Alzheimer's disease brain tissue EGCG does not, however, easily penetrate the human brain. They found two other molecules -- CNS-11 and CNS-17 -- that work like EGCG to stop tangles spreading cell to cell but are better leads for drugs.

Scientists discover how air pollution may trigger lung cancer in never-smokers

Tue, 13 Sep 2022 11:04:12 EDT

A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year.

'Drug factory' implants eliminate mesothelioma tumors in mice

Mon, 22 Aug 2022 17:49:24 EDT

Researchers have shown they can eradicate advanced-stage mesothelioma tumors in mice in just a few days with a treatment combining tiny, cytokine 'drug factory' implants and a checkpoint inhibitor drug.

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